CDK2: A Potential Target for Cancer Treatment
Cyclin-Dependent Kinase 2 Over-Activation in Cancer
Cyclin-dependent kinase 2 (CDK2), a protein complex involved in cell cycle regulation, is often over-activated in various types of cancer. This abnormal activation contributes to uncontrolled cell growth and proliferation, making CDK2 a promising target for developing novel cancer therapies.
Regulation of CDK2 Activity
CDK2 activity is regulated by cyclins, which bind to CDK2 to activate its catalytic function. Two families of CDK inhibitors further modulate this activity, ensuring proper cell cycle progression.
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